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Found
1
Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM484460'
Target
SH2B adapter protein 2
(Human)
Novartis
US Patent
Ligand
BDBM484460
(N-(3-((2-(4-Amino-4-methylpiperidin-1-yl)-3H-imida...)
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Affinity Data
IC50: 70nM
Assay Description:
The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...
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Ligand Info
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US Patent
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