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Found 1 Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM484460'
TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484460(N-(3-((2-(4-Amino-4-methylpiperidin-1-yl)-3H-imida...)
Affinity DataIC50:  70nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent