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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 8 subunit alpha' and Ligand = 'BDBM373961'
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM373961(US10246453, Example 228 | US10815229, Example 228 ...)
Affinity DataIC50:  31nMAssay Description:In general, Trex HEK293 cells were stably transfected with an inducible expression vector containing the full-length cDNA coding for the desired huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM373961(US10246453, Example 228 | US10815229, Example 228 ...)
Affinity DataIC50:  31nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent