Found 13 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM22418' TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Inhibition of [3H]DA uptake evaluated at the dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(BOVINE)
The University Of Queensland
Curated by PDSP Ki Database
The University Of Queensland
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 645nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human NETMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 830nM EC50: 385nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 830nMAssay Description:Compound was tested for inhibition of [3H]5-HT binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 1.12E+3nM EC50: 835nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 2.36E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 2.41E+3nMAssay Description:Binding affinity towards non-selective opiate receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 1.07E+4nMAssay Description:Inhibition of [3H]mazindol binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK cells expressing human NETMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 221nMAssay Description:Binding affinity towards non-selective opiate receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 385nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
