Found 3 Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 12' and Ligand = 'BDBM50206509' TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong
Curated by ChEMBL
The Chinese University Of Hong Kong
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong
Curated by ChEMBL
The Chinese University Of Hong Kong
Curated by ChEMBL
Affinity DataIC50: 8.64E+4nMAssay Description:Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong
Curated by ChEMBL
The Chinese University Of Hong Kong
Curated by ChEMBL
Affinity DataIC50: 1.74E+5nMAssay Description:URAT1 (Uric Acid Transporter 1) is expressed on the apical membrane in renal tubules. It mediates the re-uptake of uric acid from the urine into the ...More data for this Ligand-Target Pair
