Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM321312'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321312(US10179791, Compound 128 | US10807991, Compound 12...)
Affinity DataEC50: <3.16E+3nMAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321312(US10179791, Compound 128 | US10807991, Compound 12...)
Affinity DataEC50: >3.16E+3nMAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog n°: FAST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321312(US10179791, Compound 128 | US10807991, Compound 12...)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells assessed as increase in calcium flux by aequorin-derived luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed