BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Squalene synthetase' and Ligand = 'BDBM50357698'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Squalene synthetase


(Rattus norvegicus)
BDBM50357698
PNG
(CHEMBL1915485)
Show SMILES CN1CC(Oc2ccccc12)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C21H19NO/c1-22-15-21(23-20-10-6-5-9-19(20)22)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14,21H,15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.70E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal squalene synthase activity assessed as conversion of [3H]FPP to squalene


J Med Chem 54: 5583-91 (2011)


Article DOI: 10.1021/jm200763k
BindingDB Entry DOI: 10.7270/Q2X92BPZ
More data for this
Ligand-Target Pair