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Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50304872'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304872(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-3-yl)...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304872(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-3-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed