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Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 2' and Ligand = 'BDBM50278349'
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells cotransfected with GFP assessed as reduction in ADPR-induced current by whole cell patch-clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed