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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50218209'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50218209
PNG
(CHEMBL250773 | Tyrosinase Inhibitor, 3 | naphthale...)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H26N2O/c24-21(19-9-8-17-6-2-3-7-18(17)16-19)23-14-10-20(11-15-23)22-12-4-1-5-13-22/h2-3,6-9,16,20H,1,4-5,10-15H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.64E+3n/an/an/an/an/an/a



Central University of Las Villas

Curated by ChEMBL


Assay Description
Inhibition of mashroom tyrosinase


Eur J Med Chem 42: 1370-81 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.026
BindingDB Entry DOI: 10.7270/Q23R0TP1
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50218209
PNG
(CHEMBL250773 | Tyrosinase Inhibitor, 3 | naphthale...)
Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H26N2O/c24-21(19-9-8-17-6-2-3-7-18(17)16-19)23-14-10-20(11-15-23)22-12-4-1-5-13-22/h2-3,6-9,16,20H,1,4-5,10-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.64E+3n/an/an/an/a6.837



University of Karachi



Assay Description
Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...


J Enzyme Inhib Med Chem 20: 401-7 (2005)


Article DOI: 10.1080/14756360500179333
BindingDB Entry DOI: 10.7270/Q29G5KBN
More data for this
Ligand-Target Pair