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Found 6 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM377707'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  0.370nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  0.370nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  1.40nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  1.40nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  3.30nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377707(5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphen...)
Affinity DataIC50:  3.30nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent