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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM412687'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50:  1.02nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of JAK1 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed