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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50335207'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50335207(CHEMBL1650731 | N4-[5-(dimethylamino)-1H-pyrazol-3...)
Affinity DataIC50:  16nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50335207(CHEMBL1650731 | N4-[5-(dimethylamino)-1H-pyrazol-3...)
Affinity DataIC50:  815nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed