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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM153218'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153218(US8993756, 15-2)
Affinity DataIC50:  0.0200nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent