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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM305807'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM305807
(5-(4-(1-((1r,3s)-1-(Cyanomethyl)-3-methoxycyclobut...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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