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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM475679'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM475679((4aR,8aS)-8a-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataEC50:  25nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM475679((4aR,8aS)-8a-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataEC50:  15nMAssay Description:Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent