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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM350855'
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM350855(UNC2143A | US10004755, Compound UNC2143A | US97956...)
Affinity DataIC50:  0.970nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM350855(UNC2143A | US10004755, Compound UNC2143A | US97956...)
Affinity DataIC50: <250nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent