TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.740nMAssay Description:Inhibition of Mer (unknown origin) by Off-chip Mobility Shift AssayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGFR extracellular/transmembrane domain-tagged Mer intracellular domain (unknown origin) expressed in 32D cells assessed as inhibition ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Unc Eshelman School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Mer phosphorylation in human 697 cells preincubated for 1 hr by densitometryMore data for this Ligand-Target Pair