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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM255491'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255491(US10828301, Compound R940256 | US9499493, R940255 ...)
Affinity DataIC50:  771nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255491(US10828301, Compound R940256 | US9499493, R940255 ...)
Affinity DataIC50:  2.79E+3nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255491(US10828301, Compound R940256 | US9499493, R940255 ...)
Affinity DataIC50:  2.79E+3nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent