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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM255511'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255511(US10828301, Compound R935309 | US9499493, R935309)
Affinity DataIC50:  98nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255511(US10828301, Compound R935309 | US9499493, R935309)
Affinity DataIC50:  98nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent