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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM471746'
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Rigel Pharmceuticals
US Patent
Ligand
BDBM471746
(5-Fluoro-N4-(3-hydroxy-4-methylphenyl)-N2-[3-[(N-m...)
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Affinity Data
IC50: 108nM
Assay Description:
Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...
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Ligand Info
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US Patent
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