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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 2' and Ligand = 'BDBM50008923'
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant human TDP2 using 3'-labeled alpha-[32P]-cordycepin as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant human Tdp2 assessed as decrease in alpha 32P-cordycepin-3'-labeled DNA breaks after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed