BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 2' and Ligand = 'BDBM50179251'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosyl-DNA phosphodiesterase 2


(Homo sapiens (Human))
BDBM50179251
PNG
(CHEMBL3814209)
Show SMILES COc1ccc(CC2C(=O)N(N=C2C(O)=O)c2ccc(cc2)[N+]([O-])=O)cc1Oc1ccc(F)cc1
Show InChI InChI=1S/C24H18FN3O7/c1-34-20-11-2-14(13-21(20)35-18-9-3-15(25)4-10-18)12-19-22(24(30)31)26-27(23(19)29)16-5-7-17(8-6-16)28(32)33/h2-11,13,19H,12H2,1H3,(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of human TDP2


Bioorg Med Chem Lett 26: 3232-3236 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.065
BindingDB Entry DOI: 10.7270/Q22809HF
More data for this
Ligand-Target Pair