Found 4 Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme ATG7' and Ligand = 'BDBM475984' TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: <20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 431nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
