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Found 3 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM14974'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14974(CHEMBL221484 | N-(3-(3-(Dimethylamino)propyl)-5-(t...)
Affinity DataIC50:  2nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14974(CHEMBL221484 | N-(3-(3-(Dimethylamino)propyl)-5-(t...)
Affinity DataIC50:  2nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14974(CHEMBL221484 | N-(3-(3-(Dimethylamino)propyl)-5-(t...)
Affinity DataIC50:  2nMAssay Description:Inhibition of KDR after 90 mins by HTRF assayMore data for this Ligand-Target Pair