Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50240404' TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories
Curated by ChEMBL
Matrix Laboratories
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories
Curated by ChEMBL
Matrix Laboratories
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human PDE4A expressed in insect sf9 cells using [3H]-cAMP as substrateMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories
Curated by ChEMBL
Matrix Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories
Curated by ChEMBL
Matrix Laboratories
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
