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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cFMS -Tie-2 Chimera' and Ligand = 'BDBM17748'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cFMS -Tie-2 Chimera


(Homo sapiens (Human))
BDBM17748
PNG
(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Show SMILES Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3
PDB
MMDB

GoogleScholar
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 8.30E+3n/an/an/an/a7.522



Johnson & Johnson Pharmaceutical



Assay Description
The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...


J Biol Chem 282: 4085-93 (2007)


Article DOI: 10.1074/jbc.M608182200
BindingDB Entry DOI: 10.7270/Q2NK3C8N
More data for this
Ligand-Target Pair