Compile Data Set for Download or QSAR
maximum 50k data
Found 60 from Arris
TargetCoagulation factor X(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  5nM ΔG°:  -11.2kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16304(2-(1H-1,3-benzodiazol-2-ylcarbonyl)-1H-1,3-benzodi...)
Affinity DataKi:  5.20nM ΔG°:  -11.2kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  5.60nM ΔG°:  -11.1kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  23nM ΔG°:  -10.3kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16305(2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-c...)
Affinity DataKi:  23.1nM ΔG°:  -10.3kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  23.5nM ΔG°:  -10.3kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  41nM ΔG°:  -9.97kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16304(2-(1H-1,3-benzodiazol-2-ylcarbonyl)-1H-1,3-benzodi...)
Affinity DataKi:  50nM ΔG°:  -9.85kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  69.5nM ΔG°:  -9.66kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  90nM ΔG°:  -9.51kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16304(2-(1H-1,3-benzodiazol-2-ylcarbonyl)-1H-1,3-benzodi...)
Affinity DataKi:  101nM ΔG°:  -9.44kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  310nM ΔG°:  -8.78kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  321nM ΔG°:  -8.76kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16305(2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-c...)
Affinity DataKi:  666nM ΔG°:  -8.34kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  721nM ΔG°:  -8.29kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  1.60E+3nM ΔG°:  -7.82kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16305(2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-c...)
Affinity DataKi:  1.65E+3nM ΔG°:  -7.80kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  1.85E+3nM ΔG°:  -7.74kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  2.31E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  2.50E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  3.70E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16304(2-(1H-1,3-benzodiazol-2-ylcarbonyl)-1H-1,3-benzodi...)
Affinity DataKi:  5.72E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  8.04E+3nM ΔG°:  -6.88kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  8.80E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  1.00E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  1.05E+4nM ΔG°:  -6.72kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  1.10E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  1.10E+4nM ΔG°:  -6.69kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  1.35E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16305(2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-c...)
Affinity DataKi:  1.53E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  1.64E+4nM ΔG°:  -6.46kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  1.88E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  1.93E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  2.01E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  2.09E+4nM ΔG°:  -6.32kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  2.25E+4nM ΔG°:  -6.27kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  2.34E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  2.55E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16305(2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-c...)
Affinity DataKi:  2.88E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  3.10E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  3.12E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16309(2-(quinolin-8-yl)-1H-1,3-benzodiazole-6-carboximid...)
Affinity DataKi:  4.18E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16308(2-(isoquinolin-1-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  5.45E+4nM ΔG°:  -5.75kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  5.66E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16310(2-(isoquinolin-3-yl)-1H-1,3-benzodiazole-6-carboxi...)
Affinity DataKi:  6.33E+4nM ΔG°:  -5.67kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  8.15E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16304(2-(1H-1,3-benzodiazol-2-ylcarbonyl)-1H-1,3-benzodi...)
Affinity DataKi:  8.75E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Arris

LigandPNGBDBM16306(2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximida...)
Affinity DataKi:  1.01E+5nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  1.20E+5nM ΔG°:  -5.29kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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