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Compile Data Set for Download or QSAR

Found 474 hits with Last Name = 'filla' and Initial = 's'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130461
PNG
(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12
Show InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)
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1.60n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50130450
PNG
(CHEMBL104026 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2cnc(NC(C)=O)cc12
Show InChI InChI=1S/C15H20N4O/c1-10(20)18-15-7-12-13(8-16-14(12)9-17-15)11-3-5-19(2)6-4-11/h7-9,11,16H,3-6H2,1-2H3,(H,17,18,20)
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2n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130461
PNG
(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12
Show InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)
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2.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130461
PNG
(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12
Show InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)
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2.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT1F receptor by radioligand binding assay


Bioorg Med Chem Lett 25: 4337-41 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.042
BindingDB Entry DOI: 10.7270/Q2NC630T
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137539
PNG
(2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-fur...)
Show SMILES CN1CCC(CC1)c1coc2ccc(NC(=O)c3c(F)cc(F)cc3F)nc12
Show InChI InChI=1S/C20H18F3N3O2/c1-26-6-4-11(5-7-26)13-10-28-16-2-3-17(24-19(13)16)25-20(27)18-14(22)8-12(21)9-15(18)23/h2-3,8-11H,4-7H2,1H3,(H,24,25,27)
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2.30n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130471
PNG
(1-Methyl-3-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CNC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C15H21N5O/c1-16-15(21)19-13-4-3-12-14(18-13)11(9-17-12)10-5-7-20(2)8-6-10/h3-4,9-10,17H,5-8H2,1-2H3,(H2,16,18,19,21)
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2.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137540
PNG
(2-Chloro-6-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Show SMILES CN1CCC(CC1)c1coc2ccc(NC(=O)c3c(F)cccc3Cl)nc12
Show InChI InChI=1S/C20H19ClFN3O2/c1-25-9-7-12(8-10-25)13-11-27-16-5-6-17(23-19(13)16)24-20(26)18-14(21)3-2-4-15(18)22/h2-6,11-12H,7-10H2,1H3,(H,23,24,26)
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2.90n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137538
PNG
(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Show SMILES CN1CCC(CC1)c1coc2ccc(NC(=O)c3ccc(F)cc3Cl)nc12
Show InChI InChI=1S/C20H19ClFN3O2/c1-25-8-6-12(7-9-25)15-11-27-17-4-5-18(23-19(15)17)24-20(26)14-3-2-13(22)10-16(14)21/h2-5,10-12H,6-9H2,1H3,(H,23,24,26)
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3n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
Glutamate receptor AMPA 1/2


(Homo sapiens (Human))
BDBM50494356
PNG
(CHEMBL3088070)
Show SMILES Cl.OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1
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3n/an/an/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)


Bioorg Med Chem Lett 23: 6463-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.045
BindingDB Entry DOI: 10.7270/Q2XS5ZBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137541
PNG
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b...)
Show SMILES CN1CCC(CC1)c1coc2ccc(NC(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H20FN3O2/c1-24-10-8-13(9-11-24)16-12-26-17-6-7-18(22-19(16)17)23-20(25)14-2-4-15(21)5-3-14/h2-7,12-13H,8-11H2,1H3,(H,22,23,25)
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3.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Concentration required for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-1) cells expressing the human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))
BDBM50130438
PNG
(1-(4-Fluoro-phenyl)-3-[3-(1-methyl-piperidin-4-yl)...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)Nc3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H22FN5O/c1-26-10-8-13(9-11-26)16-12-22-17-6-7-18(24-19(16)17)25-20(27)23-15-4-2-14(21)3-5-15/h2-7,12-13,22H,8-11H2,1H3,(H2,23,24,25,27)
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3.20n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130422
PNG
(1-Ethyl-3-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[...)
Show SMILES CCNC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C16H23N5O/c1-3-17-16(22)20-14-5-4-13-15(19-14)12(10-18-13)11-6-8-21(2)9-7-11/h4-5,10-11,18H,3,6-9H2,1-2H3,(H2,17,19,20,22)
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3.80n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50130438
PNG
(1-(4-Fluoro-phenyl)-3-[3-(1-methyl-piperidin-4-yl)...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)Nc3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H22FN5O/c1-26-10-8-13(9-11-26)16-12-22-17-6-7-18(24-19(16)17)25-20(27)23-15-4-2-14(21)3-5-15/h2-7,12-13,22H,8-11H2,1H3,(H2,23,24,25,27)
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3.80n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130468
PNG
(2,4-Dichloro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyr...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(Cl)cc3Cl)nc12
Show InChI InChI=1S/C20H20Cl2N4O/c1-26-8-6-12(7-9-26)15-11-23-17-4-5-18(24-19(15)17)25-20(27)14-3-2-13(21)10-16(14)22/h2-5,10-12,23H,6-9H2,1H3,(H,24,25,27)
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4.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130439
PNG
(CHEMBL102250 | Furan-3-carboxylic acid [3-(1-methy...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccoc3)nc12
Show InChI InChI=1S/C18H20N4O2/c1-22-7-4-12(5-8-22)14-10-19-15-2-3-16(20-17(14)15)21-18(23)13-6-9-24-11-13/h2-3,6,9-12,19H,4-5,7-8H2,1H3,(H,20,21,23)
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4.60n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130466
PNG
(CHEMBL105556 | Methanesulfonic acid 3-(1-methyl-pi...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(OS(C)(=O)=O)nc12
Show InChI InChI=1S/C14H19N3O3S/c1-17-7-5-10(6-8-17)11-9-15-12-3-4-13(16-14(11)12)20-21(2,18)19/h3-4,9-10,15H,5-8H2,1-2H3
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4.70n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130448
PNG
(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(C)=O)nc12
Show InChI InChI=1S/C15H20N4O/c1-10(20)17-14-4-3-13-15(18-14)12(9-16-13)11-5-7-19(2)8-6-11/h3-4,9,11,16H,5-8H2,1-2H3,(H,17,18,20)
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5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50130468
PNG
(2,4-Dichloro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyr...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(Cl)cc3Cl)nc12
Show InChI InChI=1S/C20H20Cl2N4O/c1-26-8-6-12(7-9-26)15-11-23-17-4-5-18(24-19(15)17)25-20(27)14-3-2-13(21)10-16(14)22/h2-5,10-12,23H,6-9H2,1H3,(H,24,25,27)
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5.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50119543
PNG
(CHEMBL3617549)
Show SMILES CN1CCC(CC1)C(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1
Show InChI InChI=1S/C20H21FN2O2/c1-23-11-9-14(10-12-23)19(24)16-3-2-4-18(13-16)22-20(25)15-5-7-17(21)8-6-15/h2-8,13-14H,9-12H2,1H3,(H,22,25)
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5.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT1F receptor by radioligand binding assay


Bioorg Med Chem Lett 25: 4337-41 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.042
BindingDB Entry DOI: 10.7270/Q2NC630T
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130426
PNG
(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C16H22N4O/c1-3-15(21)18-14-5-4-13-16(19-14)12(10-17-13)11-6-8-20(2)9-7-11/h4-5,10-11,17H,3,6-9H2,1-2H3,(H,18,19,21)
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5.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130436
PNG
(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(C)c3)nc12
Show InChI InChI=1S/C21H24N4O/c1-14-4-3-5-16(12-14)21(26)24-19-7-6-18-20(23-19)17(13-22-18)15-8-10-25(2)11-9-15/h3-7,12-13,15,22H,8-11H2,1-2H3,(H,23,24,26)
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5.80n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130442
PNG
(CHEMBL105722 | Pyridine-2-carboxylic acid [3-(1-me...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccn3)nc12
Show InChI InChI=1S/C19H21N5O/c1-24-10-7-13(8-11-24)14-12-21-15-5-6-17(22-18(14)15)23-19(25)16-4-2-3-9-20-16/h2-6,9,12-13,21H,7-8,10-11H2,1H3,(H,22,23,25)
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6.30n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130465
PNG
(CHEMBL105955 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CCCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C17H24N4O/c1-3-4-16(22)19-15-6-5-14-17(20-15)13(11-18-14)12-7-9-21(2)10-8-12/h5-6,11-12,18H,3-4,7-10H2,1-2H3,(H,19,20,22)
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6.90n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130467
PNG
(CHEMBL321080 | Thiophene-2-carboxylic acid [3-(1-m...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccs3)nc12
Show InChI InChI=1S/C18H20N4OS/c1-22-8-6-12(7-9-22)13-11-19-14-4-5-16(20-17(13)14)21-18(23)15-3-2-10-24-15/h2-5,10-12,19H,6-9H2,1H3,(H,20,21,23)
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7.10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130432
PNG
(4-Cyano-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(cc3)C#N)nc12
Show InChI InChI=1S/C21H21N5O/c1-26-10-8-15(9-11-26)17-13-23-18-6-7-19(24-20(17)18)25-21(27)16-4-2-14(12-22)3-5-16/h2-7,13,15,23H,8-11H2,1H3,(H,24,25,27)
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7.20n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130445
PNG
(CHEMBL105743 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3)nc12
Show InChI InChI=1S/C20H22N4O/c1-24-11-9-14(10-12-24)16-13-21-17-7-8-18(22-19(16)17)23-20(25)15-5-3-2-4-6-15/h2-8,13-14,21H,9-12H2,1H3,(H,22,23,25)
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7.30n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130447
PNG
(CHEMBL104753 | Thiophene-3-carboxylic acid [3-(1-m...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccsc3)nc12
Show InChI InChI=1S/C18H20N4OS/c1-22-7-4-12(5-8-22)14-10-19-15-2-3-16(20-17(14)15)21-18(23)13-6-9-24-11-13/h2-3,6,9-12,19H,4-5,7-8H2,1H3,(H,20,21,23)
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7.40n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130463
PNG
(4-Fluoro-benzenesulfonic acid 3-(1-methyl-piperidi...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(OS(=O)(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C19H20FN3O3S/c1-23-10-8-13(9-11-23)16-12-21-17-6-7-18(22-19(16)17)26-27(24,25)15-4-2-14(20)3-5-15/h2-7,12-13,21H,8-11H2,1H3
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7.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130443
PNG
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H21FN4O/c1-25-10-8-13(9-11-25)16-12-22-17-6-7-18(23-19(16)17)24-20(26)14-2-4-15(21)5-3-14/h2-7,12-13,22H,8-11H2,1H3,(H,23,24,26)
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7.60n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130443
PNG
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H21FN4O/c1-25-10-8-13(9-11-25)16-12-22-17-6-7-18(23-19(16)17)24-20(26)14-2-4-15(21)5-3-14/h2-7,12-13,22H,8-11H2,1H3,(H,23,24,26)
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7.60n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130451
PNG
(CHEMBL104692 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(cc3)[N+]([O-])=O)nc12
Show InChI InChI=1S/C20H21N5O3/c1-24-10-8-13(9-11-24)16-12-21-17-6-7-18(22-19(16)17)23-20(26)14-2-4-15(5-3-14)25(27)28/h2-7,12-13,21H,8-11H2,1H3,(H,22,23,26)
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7.70n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50130466
PNG
(CHEMBL105556 | Methanesulfonic acid 3-(1-methyl-pi...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(OS(C)(=O)=O)nc12
Show InChI InChI=1S/C14H19N3O3S/c1-17-7-5-10(6-8-17)11-9-15-12-3-4-13(16-14(11)12)20-21(2,18)19/h3-4,9-10,15H,5-8H2,1-2H3
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8n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137542
PNG
(CHEMBL178066 | N-[3-(2-Dimethylamino-ethyl)-2-meth...)
Show SMILES CN(C)CCc1c(C)[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12
Show InChI InChI=1S/C20H22FN3O/c1-13-17(10-11-24(2)3)18-12-16(8-9-19(18)22-13)23-20(25)14-4-6-15(21)7-5-14/h4-9,12,22H,10-11H2,1-3H3,(H,23,25)
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8.20n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50119542
PNG
(CHEMBL3617550)
Show SMILES CN1CCC(CC1)C(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1F
Show InChI InChI=1S/C20H20F2N2O2/c1-24-11-9-13(10-12-24)19(25)16-3-2-4-17(18(16)22)23-20(26)14-5-7-15(21)8-6-14/h2-8,13H,9-12H2,1H3,(H,23,26)
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8.30n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT1F receptor by radioligand binding assay


Bioorg Med Chem Lett 25: 4337-41 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.042
BindingDB Entry DOI: 10.7270/Q2NC630T
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130437
PNG
(CHEMBL105958 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccncc3)nc12
Show InChI InChI=1S/C19H21N5O/c1-24-10-6-13(7-11-24)15-12-21-16-2-3-17(22-18(15)16)23-19(25)14-4-8-20-9-5-14/h2-5,8-9,12-13,21H,6-7,10-11H2,1H3,(H,22,23,25)
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8.40n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50130471
PNG
(1-Methyl-3-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CNC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C15H21N5O/c1-16-15(21)19-13-4-3-12-14(18-13)11(9-17-12)10-5-7-20(2)8-6-10/h3-4,9-10,17H,5-8H2,1-2H3,(H2,16,18,19,21)
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8.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130433
PNG
(CHEMBL420475 | Cyclobutanecarboxylic acid [3-(1-me...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)C3CCC3)nc12
Show InChI InChI=1S/C18H24N4O/c1-22-9-7-12(8-10-22)14-11-19-15-5-6-16(20-17(14)15)21-18(23)13-3-2-4-13/h5-6,11-13,19H,2-4,7-10H2,1H3,(H,20,21,23)
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8.70n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50119532
PNG
(CHEMBL3617557)
Show SMILES CN1CCC(CC1)C(=O)c1cccc(NC(=O)c2ccc(F)cc2)n1
Show InChI InChI=1S/C19H20FN3O2/c1-23-11-9-13(10-12-23)18(24)16-3-2-4-17(21-16)22-19(25)14-5-7-15(20)8-6-14/h2-8,13H,9-12H2,1H3,(H,21,22,25)
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9.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT1F receptor by radioligand binding assay


Bioorg Med Chem Lett 25: 4337-41 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.042
BindingDB Entry DOI: 10.7270/Q2NC630T
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130449
PNG
(4-Fluoro-N-(3-piperidin-4-yl-1H-pyrrolo[3,2-b]pyri...)
Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc2[nH]cc(C3CCNCC3)c2n1
Show InChI InChI=1S/C19H19FN4O/c20-14-3-1-13(2-4-14)19(25)24-17-6-5-16-18(23-17)15(11-22-16)12-7-9-21-10-8-12/h1-6,11-12,21-22H,7-10H2,(H,23,24,25)
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9.5n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130427
PNG
(CHEMBL103424 | N-[3-(1-Methyl-piperidin-4-yl)-1H-i...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(C)=O)cc12
Show InChI InChI=1S/C16H21N3O/c1-11(20)18-13-3-4-16-14(9-13)15(10-17-16)12-5-7-19(2)8-6-12/h3-4,9-10,12,17H,5-8H2,1-2H3,(H,18,20)
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9.70n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130440
PNG
(CHEMBL104720 | Cyclopropanecarboxylic acid [3-(1-m...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)C3CC3)nc12
Show InChI InChI=1S/C17H22N4O/c1-21-8-6-11(7-9-21)13-10-18-14-4-5-15(19-16(13)14)20-17(22)12-2-3-12/h4-5,10-12,18H,2-3,6-9H2,1H3,(H,19,20,22)
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9.80n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130435
PNG
(3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12
Show InChI InChI=1S/C20H21FN4O/c1-25-9-7-13(8-10-25)16-12-22-17-5-6-18(23-19(16)17)24-20(26)14-3-2-4-15(21)11-14/h2-6,11-13,22H,7-10H2,1H3,(H,23,24,26)
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11n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130446
PNG
(CHEMBL321967 | Cyclopentanecarboxylic acid [3-(1-m...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)C3CCCC3)nc12
Show InChI InChI=1S/C19H26N4O/c1-23-10-8-13(9-11-23)15-12-20-16-6-7-17(21-18(15)16)22-19(24)14-4-2-3-5-14/h6-7,12-14,20H,2-5,8-11H2,1H3,(H,21,22,24)
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11n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130438
PNG
(1-(4-Fluoro-phenyl)-3-[3-(1-methyl-piperidin-4-yl)...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)Nc3ccc(F)cc3)nc12
Show InChI InChI=1S/C20H22FN5O/c1-26-10-8-13(9-11-26)16-12-22-17-6-7-18(24-19(16)17)25-20(27)23-15-4-2-14(21)3-5-15/h2-7,12-13,22H,8-11H2,1H3,(H2,23,24,25,27)
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11n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130421
PNG
(3-Cyano-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(c3)C#N)nc12
Show InChI InChI=1S/C21H21N5O/c1-26-9-7-15(8-10-26)17-13-23-18-5-6-19(24-20(17)18)25-21(27)16-4-2-3-14(11-16)12-22/h2-6,11,13,15,23H,7-10H2,1H3,(H,24,25,27)
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11n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130458
PNG
(2-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3C)nc12
Show InChI InChI=1S/C21H24N4O/c1-14-5-3-4-6-16(14)21(26)24-19-8-7-18-20(23-19)17(13-22-18)15-9-11-25(2)12-10-15/h3-8,13,15,22H,9-12H2,1-2H3,(H,23,24,26)
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12n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130452
PNG
(4-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(C)cc3)nc12
Show InChI InChI=1S/C21H24N4O/c1-14-3-5-16(6-4-14)21(26)24-19-8-7-18-20(23-19)17(13-22-18)15-9-11-25(2)12-10-15/h3-8,13,15,22H,9-12H2,1-2H3,(H,23,24,26)
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12n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130420
PNG
(CHEMBL105091 | Furan-2-carboxylic acid [3-(1-methy...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccco3)nc12
Show InChI InChI=1S/C18H20N4O2/c1-22-8-6-12(7-9-22)13-11-19-14-4-5-16(20-17(13)14)21-18(23)15-3-2-10-24-15/h2-5,10-12,19H,6-9H2,1H3,(H,20,21,23)
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13n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130456
PNG
(CHEMBL102344 | Hexanoic acid [3-(1-methyl-piperidi...)
Show SMILES CCCCCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C19H28N4O/c1-3-4-5-6-18(24)21-17-8-7-16-19(22-17)15(13-20-16)14-9-11-23(2)12-10-14/h7-8,13-14,20H,3-6,9-12H2,1-2H3,(H,21,22,24)
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13n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130431
PNG
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Show SMILES CN1CCC(CC1)c1c[nH]c2cnc(NC(=O)c3ccc(F)cc3)cc12
Show InChI InChI=1S/C20H21FN4O/c1-25-8-6-13(7-9-25)17-11-22-18-12-23-19(10-16(17)18)24-20(26)14-2-4-15(21)5-3-14/h2-5,10-13,22H,6-9H2,1H3,(H,23,24,26)
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13n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
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