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Compile Data Set for Download or QSAR

Found 184 hits with Last Name = 'pridal' and Initial = 'l'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146832
PNG
(1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-pip...)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C21H32N2O4/c1-5-17(6-2)22-11-13-23(14-12-22)21(25)10-8-18(24)16-7-9-19(26-3)20(15-16)27-4/h7,9,15,17H,5-6,8,10-14H2,1-4H3
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0.380n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370330
PNG
(CHEMBL1202893)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(F)c1
Show InChI InChI=1S/C20H29FN2O3/c1-4-16(5-2)22-10-12-23(13-11-22)20(25)9-7-18(24)15-6-8-19(26-3)17(21)14-15/h6,8,14,16H,4-5,7,9-13H2,1-3H3
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0.430n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146836
PNG
(1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-propyl)-pip...)
Show SMILES CCC(C)(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H27ClN2O2/c1-4-19(2,3)22-13-11-21(12-14-22)18(24)10-9-17(23)15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3
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0.540n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM22541
PNG
(CLOBENPROPIT | Clobenpropit | N''-[(4-chlorophenyl...)
Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1
Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)
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0.580n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370328
PNG
(CHEMBL1202892)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(cc1)C#N
Show InChI InChI=1S/C19H27N3O2/c1-3-17(4-2)21-10-12-22(13-11-21)19(23)9-14-24-18-7-5-16(15-20)6-8-18/h5-8,17H,3-4,9-14H2,1-2H3
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0.740n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146838
PNG
(1-(4-Chloro-phenyl)-4-[4-(1-ethyl-propyl)-piperazi...)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H27ClN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3
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0.860n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370331
PNG
(CHEMBL1202896)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)N(C)C
Show InChI InChI=1S/C19H31N3O/c1-5-17(6-2)21-11-13-22(14-12-21)19(23)15-16-7-9-18(10-8-16)20(3)4/h7-10,17H,5-6,11-15H2,1-4H3
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0.960n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146840
PNG
(3-(4-Chloro-phenoxy)-1-[4-(1-ethyl-propyl)-piperaz...)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C18H27ClN2O2/c1-3-16(4-2)20-10-12-21(13-11-20)18(22)9-14-23-17-7-5-15(19)6-8-17/h5-8,16H,3-4,9-14H2,1-2H3
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1.20n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146835
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-y...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C19H25ClN2O2/c20-16-7-5-15(6-8-16)18(23)9-10-19(24)22-13-11-21(12-14-22)17-3-1-2-4-17/h5-8,17H,1-4,9-14H2
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1.20n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146826
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclobutyl-piperazin-1-yl...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCC1
Show InChI InChI=1S/C18H23ClN2O2/c19-15-6-4-14(5-7-15)17(22)8-9-18(23)21-12-10-20(11-13-21)16-2-1-3-16/h4-7,16H,1-3,8-13H2
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1.20n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370336
PNG
(CHEMBL1202903)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H27F3N2O2/c1-3-17(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-16(8-6-15)20(21,22)23/h5-8,17H,3-4,9-14H2,1-2H3
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1.40n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370338
PNG
(CHEMBL1202904)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(F)cc1
Show InChI InChI=1S/C19H27FN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3
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1.5n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370327
PNG
(CHEMBL1202901)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C18H25F3N2O/c1-3-16(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-15(8-6-14)18(19,20)21/h5-8,16H,3-4,9-13H2,1-2H3
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2.30n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370326
PNG
(CHEMBL1202900)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C18H25F3N2O2/c1-3-15(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-16(8-6-14)25-18(19,20)21/h5-8,15H,3-4,9-13H2,1-2H3
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2.60n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370329
PNG
(CHEMBL1202894)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C20H27F3N2O3/c1-3-16(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-17(8-6-15)28-20(21,22)23/h5-8,16H,3-4,9-14H2,1-2H3
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2.70n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM22904
PNG
((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Show SMILES C[C@@H](N)Cc1cnc[nH]1
Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1
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2.70n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370339
PNG
(CHEMBL1202899)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H30N2O/c1-3-22(4-2)24-14-16-25(17-15-24)23(26)18-19-10-12-21(13-11-19)20-8-6-5-7-9-20/h5-13,22H,3-4,14-18H2,1-2H3
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2.90n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146843
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclohexyl-piperazin-1-yl...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C20H27ClN2O2/c21-17-8-6-16(7-9-17)19(24)10-11-20(25)23-14-12-22(13-15-23)18-4-2-1-3-5-18/h6-9,18H,1-5,10-15H2
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3.60n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146839
PNG
(1-(4-Chloro-phenyl)-4-(4-isopropyl-piperazin-1-yl)...)
Show SMILES CC(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C17H23ClN2O2/c1-13(2)19-9-11-20(12-10-19)17(22)8-7-16(21)14-3-5-15(18)6-4-14/h3-6,13H,7-12H2,1-2H3
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4.40n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146820
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclopropylmethyl-piperaz...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC2CC2)CC1
Show InChI InChI=1S/C18H23ClN2O2/c19-16-5-3-15(4-6-16)17(22)7-8-18(23)21-11-9-20(10-12-21)13-14-1-2-14/h3-6,14H,1-2,7-13H2
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8.30n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370337
PNG
(CHEMBL1202902)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C19H27F3N2O/c1-3-17(4-2)23-11-13-24(14-12-23)18(25)10-7-15-5-8-16(9-6-15)19(20,21)22/h5-6,8-9,17H,3-4,7,10-14H2,1-2H3
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8.5n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146818
PNG
(1-(4-Chloro-phenyl)-4-[4-(tetrahydro-pyran-4-yl)-p...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCOCC1
Show InChI InChI=1S/C19H25ClN2O3/c20-16-3-1-15(2-4-16)18(23)5-6-19(24)22-11-9-21(10-12-22)17-7-13-25-14-8-17/h1-4,17H,5-14H2
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9.20n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146829
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclopropyl-piperazin-1-y...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CC1
Show InChI InChI=1S/C17H21ClN2O2/c18-14-3-1-13(2-4-14)16(21)7-8-17(22)20-11-9-19(10-12-20)15-5-6-15/h1-4,15H,5-12H2
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13.3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM22914
PNG
(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1
Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)
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14n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370334
PNG
(CHEMBL1202897)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(C)=O
Show InChI InChI=1S/C19H28N2O2/c1-4-18(5-2)20-10-12-21(13-11-20)19(23)14-16-6-8-17(9-7-16)15(3)22/h6-9,18H,4-5,10-14H2,1-3H3
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24n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146842
PNG
(1-(4-Chloro-phenyl)-4-(4-cycloheptyl-piperazin-1-y...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCCC1
Show InChI InChI=1S/C21H29ClN2O2/c22-18-9-7-17(8-10-18)20(25)11-12-21(26)24-15-13-23(14-16-24)19-5-3-1-2-4-6-19/h7-10,19H,1-6,11-16H2
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34n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146837
PNG
(1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-prop-2-ynyl...)
Show SMILES CC(C)(C#C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O2/c1-4-19(2,3)22-13-11-21(12-14-22)18(24)10-9-17(23)15-5-7-16(20)8-6-15/h1,5-8H,9-14H2,2-3H3
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89n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370335
PNG
(CHEMBL1202895)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C17H23F3N2O2/c1-3-14(4-2)21-9-11-22(12-10-21)16(23)13-5-7-15(8-6-13)24-17(18,19)20/h5-8,14H,3-4,9-12H2,1-2H3
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93n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM27213
PNG
(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Show SMILES O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1
Show InChI InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)
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94n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50370332
PNG
(CHEMBL1202898)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)COc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C18H25F3N2O3/c1-3-14(4-2)22-9-11-23(12-10-22)17(24)13-25-15-5-7-16(8-6-15)26-18(19,20)21/h5-8,14H,3-4,9-13H2,1-2H3
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110n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146819
PNG
(1-(4-Chloro-phenyl)-4-(4-cyclooctyl-piperazin-1-yl...)
Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCCCC1
Show InChI InChI=1S/C22H31ClN2O2/c23-19-10-8-18(9-11-19)21(26)12-13-22(27)25-16-14-24(15-17-25)20-6-4-2-1-3-5-7-20/h8-11,20H,1-7,12-17H2
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450n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146841
PNG
(1-(4-Chloro-phenyl)-4-[4-(1-propyl-butyl)-piperazi...)
Show SMILES CCCC(CCC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H31ClN2O2/c1-3-5-19(6-4-2)23-13-15-24(16-14-23)21(26)12-11-20(25)17-7-9-18(22)10-8-17/h7-10,19H,3-6,11-16H2,1-2H3
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480n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50146844
PNG
(1-[4-(2-Chloro-allyl)-piperazin-1-yl]-4-(4-chloro-...)
Show SMILES ClC(=C)CN1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C17H20Cl2N2O2/c1-13(18)12-20-8-10-21(11-9-20)17(23)7-6-16(22)14-2-4-15(19)5-3-14/h2-5H,1,6-12H2
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1.10E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1


(Homo sapiens (Human))
BDBM50118351
PNG
((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...)
Show SMILES CC1(CCC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1
Show InChI InChI=1S/C10H12ClN3O2S2/c1-10(3-2-4-10)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,2-4H2,1H3,(H2,12,13,14)
PDB

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n/an/a 3n/an/an/an/an/an/a



Novo Nordisk Research and Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...


J Med Chem 45: 4171-87 (2002)


Article DOI: 10.1021/jm0208121
BindingDB Entry DOI: 10.7270/Q2SF2VGM
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202031
PNG
(3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1
Show InChI InChI=1S/C30H29Cl2N3O4/c31-24-16-25(32)18-26(17-24)34-30(39)35(27-12-10-22(11-13-27)21-4-2-1-3-5-21)19-20-6-8-23(9-7-20)29(38)33-15-14-28(36)37/h4,6-13,16-18H,1-3,5,14-15,19H2,(H,33,38)(H,34,39)(H,36,37)
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n/an/a 27n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29124
PNG
(aminothiazole, 21)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(SC(F)(F)F)cc2)cc1
Show InChI InChI=1S/C28H21F6N3O3S2/c29-27(30,31)20-7-5-18(6-8-20)23-16-41-26(36-23)37(21-9-11-22(12-10-21)42-28(32,33)34)15-17-1-3-19(4-2-17)25(40)35-14-13-24(38)39/h1-12,16H,13-15H2,(H,35,40)(H,38,39)
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n/an/a 34n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202047
PNG
(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-isopropylph...)
Show SMILES CC(C)c1ccc(NC(=O)N(Cc2ccc(cc2)C(=O)NCCC(O)=O)[C@H]2CC[C@@H](CC2)C(C)(C)C)cc1
Show InChI InChI=1S/C31H43N3O4/c1-21(2)23-10-14-26(15-11-23)33-30(38)34(27-16-12-25(13-17-27)31(3,4)5)20-22-6-8-24(9-7-22)29(37)32-19-18-28(35)36/h6-11,14-15,21,25,27H,12-13,16-20H2,1-5H3,(H,32,37)(H,33,38)(H,35,36)/t25-,27-
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n/an/a 35n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29106
PNG
(aminothiazole, 3)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(OC(F)(F)F)cc2)c2ccc(cc2)C2=CCCCC2)cc1
Show InChI InChI=1S/C33H30F3N3O4S/c34-33(35,36)43-28-16-12-25(13-17-28)29-21-44-32(38-29)39(27-14-10-24(11-15-27)23-4-2-1-3-5-23)20-22-6-8-26(9-7-22)31(42)37-19-18-30(40)41/h4,6-17,21H,1-3,5,18-20H2,(H,37,42)(H,40,41)
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n/an/a 36n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202056
PNG
(CHEMBL219244 | cis-3-{4-[1-(4-tert-butylcyclohexyl...)
Show SMILES CC(C)(C)[C@@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23+
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n/an/a 47n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29107
PNG
(aminothiazole, 4)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(cc2)C2=CCCCC2)cc1
Show InChI InChI=1S/C33H30F3N3O3S/c34-33(35,36)27-14-10-25(11-15-27)29-21-43-32(38-29)39(28-16-12-24(13-17-28)23-4-2-1-3-5-23)20-22-6-8-26(9-7-22)31(42)37-19-18-30(40)41/h4,6-17,21H,1-3,5,18-20H2,(H,37,42)(H,40,41)
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n/an/a 48n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29109
PNG
(aminothiazole, 6)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(OC(F)(F)F)cc2)c2ccc-3c(Cc4ccccc-34)c2)cc1
Show InChI InChI=1S/C34H26F3N3O4S/c35-34(36,37)44-27-12-9-22(10-13-27)30-20-45-33(39-30)40(19-21-5-7-23(8-6-21)32(43)38-16-15-31(41)42)26-11-14-29-25(18-26)17-24-3-1-2-4-28(24)29/h1-14,18,20H,15-17,19H2,(H,38,43)(H,41,42)
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n/an/a 50n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50144009
PNG
(3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...)
Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23-
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n/an/a 55n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202041
PNG
(CHEMBL375167 | trans-3-{4-[3-(3,5-Bis(trifluoromet...)
Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H35F6N3O4/c1-28(2,3)20-8-10-24(11-9-20)39(17-18-4-6-19(7-5-18)26(42)37-13-12-25(40)41)27(43)38-23-15-21(29(31,32)33)14-22(16-23)30(34,35)36/h4-7,14-16,20,24H,8-13,17H2,1-3H3,(H,37,42)(H,38,43)(H,40,41)/t20-,24-
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n/an/a 56n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202051
PNG
(CHEMBL373824 | trans-3-(4-((1-(4-tert-butylcyclohe...)
Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1C#N
Show InChI InChI=1S/C30H35F3N4O5/c1-29(2,3)22-8-10-23(11-9-22)37(18-19-4-6-20(7-5-19)27(40)35-15-14-26(38)39)28(41)36-25-13-12-24(16-21(25)17-34)42-30(31,32)33/h4-7,12-13,16,22-23H,8-11,14-15,18H2,1-3H3,(H,35,40)(H,36,41)(H,38,39)/t22-,23-
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n/an/a 56n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Rattus norvegicus)
BDBM50144009
PNG
(3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...)
Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23-
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n/an/a 56n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of rat glucagon receptor


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202029
PNG
(3-(4-((1-(4-isopropylcyclohexyl)-3-(4-(trifluorome...)
Show SMILES CC(C)C1CCC(CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C28H34F3N3O5/c1-18(2)20-7-11-23(12-8-20)34(27(38)33-22-9-13-24(14-10-22)39-28(29,30)31)17-19-3-5-21(6-4-19)26(37)32-16-15-25(35)36/h3-6,9-10,13-14,18,20,23H,7-8,11-12,15-17H2,1-2H3,(H,32,37)(H,33,38)(H,35,36)
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n/an/a 59n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50202039
PNG
(3-(4-((1-(4-cyclohexylphenyl)-3-(4-(trifluorometho...)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2ccc(OC(F)(F)F)cc2)c2ccc(cc2)C2CCCCC2)cc1
Show InChI InChI=1S/C31H32F3N3O5/c32-31(33,34)42-27-16-12-25(13-17-27)36-30(41)37(26-14-10-23(11-15-26)22-4-2-1-3-5-22)20-21-6-8-24(9-7-21)29(40)35-19-18-28(38)39/h6-17,22H,1-5,18-20H2,(H,35,40)(H,36,41)(H,38,39)
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n/an/a 61n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human cloned glucagon receptor expressed in BHK cells


J Med Chem 50: 113-28 (2007)


Article DOI: 10.1021/jm058026u
BindingDB Entry DOI: 10.7270/Q26M36GK
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29119
PNG
(aminothiazole, 16)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C27H21ClF3N3O3S/c28-21-9-11-22(12-10-21)34(15-17-1-3-19(4-2-17)25(37)32-14-13-24(35)36)26-33-23(16-38-26)18-5-7-20(8-6-18)27(29,30)31/h1-12,16H,13-15H2,(H,32,37)(H,35,36)
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n/an/a 76n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29114
PNG
(aminothiazole, 11)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc3CCCCc3c2)cc1
Show InChI InChI=1S/C31H28F3N3O3S/c32-31(33,34)25-12-9-22(10-13-25)27-19-41-30(36-27)37(26-14-11-21-3-1-2-4-24(21)17-26)18-20-5-7-23(8-6-20)29(40)35-16-15-28(38)39/h5-14,17,19H,1-4,15-16,18H2,(H,35,40)(H,38,39)
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PubMed
n/an/a 77n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM29128
PNG
(aminothiazole, 25)
Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)N(Cc1ccc-2c(Cc3ccccc-23)c1)c1nc(cs1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C34H26F3N3O3S/c35-34(36,37)26-10-6-22(7-11-26)30-20-44-33(39-30)40(27-12-8-23(9-13-27)32(43)38-16-15-31(41)42)19-21-5-14-29-25(17-21)18-24-3-1-2-4-28(24)29/h1-14,17,20H,15-16,18-19H2,(H,38,43)(H,41,42)
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PubMed
n/an/a 78n/an/an/an/a7.522



Novo Nordisk A/S



Assay Description
Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...


J Med Chem 52: 2989-3000 (2009)


Article DOI: 10.1021/jm8016249
BindingDB Entry DOI: 10.7270/Q21Z42RS
More data for this
Ligand-Target Pair
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