Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 102568
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM102568(US8536172, I-17)
Affinity DataIC50:  8.5nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM102568(US8536172, I-17)
Affinity DataIC50:  12nMAssay Description:Inhibition of human JNK1alpha1 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM102568(US8536172, I-17)
Affinity DataIC50:  47.7nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102568(US8536172, I-17)
Affinity DataIC50:  66nMAssay Description:Inhibition of human JNK2alpha2 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102568(US8536172, I-17)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of JNK-mediated c-Jun activation in TNFalpha-induced human SW1353 cells preincubated for 30 mins prior to TNFalpha treatment measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed