Found 88 of ic50 for monomerid = 10620 
Affinity DataKi: 1.31E+5nM IC50: 5.34E+3nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant butyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human BChE by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of equine BuChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BChE in human serum assessed as hydrolysis of butyrylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate incubated for 25 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human serum BuchE after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 90 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 301nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory concentration against butyrylcholinesterase was determined using rat serum homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 499nMAssay Description:Inhibition of equine serum butyrylcholine esterase incubated for 15 mins using S-butyrylthiocholine chloride substrate by colorimetric Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of bovine AChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 832nMAssay Description:Inhibition of horse serum BChE preincubated for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of Swiss albino mouse RBC AChE after 30 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:For rat AChE or BuChE inhibition assays, a reaction mixture (100 μL) containing acetylthiocholine iodide (1 mmol/L, 30 μL) (J&K Scientific)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 90 mins before substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse serum BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMpH: 8.0 T: 2°CAssay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2.0 uni...More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of equine serum BChE using butylthiocholine chloride as substrate incubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of equine serum BChE using BTC as substrate preincubated for 15 mins followed by substrate addition measured at 1 min intervals by Ellman ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:In vitro inhibitory concentration against rat cortex acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of human recombinant AchE after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
