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Found 4 of ki for monomerid = 108418
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  0.900nM IC50:  17.1nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  4nM IC50:  7nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  16nM IC50:  38nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  49.8nM IC50:  94.6nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent