Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 for monomerid = 11022
TargetSecreted chorismate mutase(Mycobacterium tuberculosis H37Rv)
Birla Institute Of Technology

LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.08E+3nMT: 2°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant MAO-B assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant human MAO-B using using kynuramine as substrate assessed as inhibition of 4-hydroxyquinoline formation incubated for 20 min...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of recombinant human MAO-A using using kynuramine as substrate assessed as inhibition of 4-hydroxyquinoline formation incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of human recombinant MAO-A assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in insect cells by fluorescence assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human MAOB by fluorimetryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramin...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  2.11E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BT1-TN-5B1-4 cells assessed as inhibition of production of hydrogen peroxide ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in insect cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  3.44E+4nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as reduc...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  5.62E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50:  3.68E+5nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
The Behrend College

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The Behrend College

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed