Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 for monomerid = 12341
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  172nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  7.44E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  1.53E+4nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  5.22E+4nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  5.22E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  5.70E+4nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  5.87E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  5.87E+4nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  7.75E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  7.75E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  1.68E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  1.97E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  2.08E+5nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  2.33E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  2.56E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed