Compile Data Set for Download or QSAR
maximum 50k data
Found 27 of ic50 for monomerid = 13058
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.5nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of STS in human T47D cells preincubated for 1 hr followed by addition of [3H]-E1S/E1S as substrate measured after 24 hrs by HPLC based rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate incubated for 20 hrs by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  2.10nMAssay Description:Irreversible inhibition of STS in human T47D cells preincubated for 2 hrs followed by compound washout and addition of [3H]-E1S/E1S as substrate meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  2.60nMAssay Description:Irreversible inhibition of STS in human T47D cells using [3H]E1S as substrate measured after 24 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of STS in human T47D cells using [3H]E1S as substrate measured after 24 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cell lysates using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of STS in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of placental microsomal estrone sulfatase (unknown origin) using [3H]-estrone sulphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of steroid sulfatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human placental microsomal STS assessed as formation of E1 preincubated for 30 mins followed by addition of E1S as substrate measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  17nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  22nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  25nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  210nMAssay Description:Compound was evaluated for its inhibitory activity against estrone sulfatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  300nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  350nMAssay Description:Irreversible inhibition of steroid sulfatase in human intact MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of steroid sulfatase in human intact MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  421nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells assessed as [14C]-Estrone formation using [3H]E1S as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed