Compile Data Set for Download or QSAR
maximum 50k data
Found 32 of ic50 for monomerid = 142598
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  3nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  5nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMT: 2°CAssay Description:The enzyme inhibitory activity of compound was determined by FRET using synthetic peptides labelled with both donor and acceptor fluorophores (Z-LY...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:p38 MAPKα: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by det...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:p38 MAPKα: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both do...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  42nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  42nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  42nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  42nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  42nMAssay Description:The inhibitory activities of compounds of the invention against Syk enzymes (Invitrogen), are evaluated in a similar fashion to that described herein...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:The inhibitory activities of test compounds against the GSK 3α enzyme isoform (Invitrogen), were evaluated by determining the level of activatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:GSK 3α: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both donor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:GSK 3α: The inhibitory activities of test compounds against the GSK 3α enzyme isoform (Invitrogen), were evaluated by determining the level...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
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US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMAssay Description:p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMAssay Description:p38 MAPKγ: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both do...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMT: 2°CAssay Description:The enzyme inhibitory activity of compound was determined by FRET using synthetic peptides labelled with both donor and acceptor fluorophores (Z-LY...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  344nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In DepthDetails US Patent