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Found 19 of ic50 for monomerid = 14362
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of cAMP PDE III enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of fraction III of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  3.80E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of fraction II of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  3.40E+6nMAssay Description:Inhibition of fraction I of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed