Compile Data Set for Download or QSAR
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Found 4 of ki for monomerid = 149919
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149919(US8975415, RP200 | US8975415, RP202 | US9242973, R...)
Affinity DataKi:  92.1nM ΔG°:  -9.59kcal/mole IC50:  128nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149919(US8975415, RP200 | US8975415, RP202 | US9242973, R...)
Affinity DataKi:  92.1nM IC50:  128nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149919(US8975415, RP200 | US8975415, RP202 | US9242973, R...)
Affinity DataKi:  113nM ΔG°:  -9.47kcal/mole IC50:  145nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149919(US8975415, RP200 | US8975415, RP202 | US9242973, R...)
Affinity DataKi:  113nM IC50:  145nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent