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Found 5 of ic50 for monomerid = 158157
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM158157(US10081622, Compound 18 | US9029356, 18 | US925508...)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant ALK (unknown origin) in presence of gamma33-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM158157(US10081622, Compound 18 | US9029356, 18 | US925508...)
Affinity DataIC50:  1.77E+3nMpH: 7.5Assay Description:ALK enzyme needs pre-activation in order to linearize reaction kinetics.Kinase Buffer (KB) for ALKKinase buffer was composed of 50 mM HEPES pH 7.5 co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM158157(US10081622, Compound 18 | US9029356, 18 | US925508...)
Affinity DataIC50:  3.23E+3nMAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.A spe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInsulin receptor(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM158157(US10081622, Compound 18 | US9029356, 18 | US925508...)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of IR (unknown origin) in presence of gamma33-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM158157(US10081622, Compound 18 | US9029356, 18 | US925508...)
Affinity DataIC50:  6.07E+3nMAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.A spe...More data for this Ligand-Target Pair
In DepthDetails US Patent