Compile Data Set for Download or QSAR
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Found 8 of ic50 for monomerid = 160077
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human P2X7 receptor expressed in 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux after 30 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50: <1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50: <1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50: <1nMpH: 7.4Assay Description:Ca2+ Flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50:  316nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50:  316nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50:  316nMpH: 7.4Assay Description:Ca2+ Flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM160077(US10047092, 18 | US10053463, 18 | US9040534, 18)
Affinity DataIC50:  350nMAssay Description:Antagonist activity at rat P2X7 receptor expressed in 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux after 30 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed