Found 122 of ec50 for drug = Activella 
Affinity DataEC50: 0.00400nMAssay Description:Activation of human ERalpha expressed in human U2-OS cells by luciferase reporter gene assay relative to untreated controlMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 0.00700nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00840nMAssay Description:Agonist activity at human ERalpha in human MCF7 cells assessed as progesterone receptor endogenous genes activation after 24 hrs by qPCRMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Effect on ERalpha in MCF7 cell line transfected with ER responsive luciferase reporterMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Activation of human ERbeta expressed in human U2-OS cells by luciferase reporter gene assay relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Percent agonistic activity for estrogen-induced pS2 expression in MCF-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0180nMAssay Description:Transcriptional potency (EC50) at Human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0190nMAssay Description:Transcriptional activation of estrogen receptor alpha in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-3...More data for this Ligand-Target Pair
Affinity DataIC50: 24nM EC50: 0.0200nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Activation of human ERbeta assessed as induction of transcriptional activation incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at human native full length ERbeta by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at full length ERbeta (unknown origin) after 24 hrs by cell based ERE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0240nMAssay Description:Agonist activity at human ERalpha expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Estrogenic activity at ERbeta (unknown origin) expressed in human MDA-MB-231/beta41 cells after 18 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Activation of human ERbeta assessed as induction of transcriptional activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Estrogenic activity at ERalpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-nitrophenol as substrate treate...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0301nMAssay Description:Induction of pS2 Gene expression in human MCF-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0360nMAssay Description:Transcriptional activation of ERbeta receptor expressed in CHO-K1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0390nMAssay Description:Transcriptional potency (EC50) at Human estrogen receptor BetaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMAssay Description:Agonist activity at human ERbeta receptor expressed in HEK293T cells transfected with pGL4.27-(ERE)3-Luc assessed as transcriptional activation measu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0460nMAssay Description:Agonist activity at ERalpha expressed in HEK cells co-expressing beta-lactamase after 18 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0470nMAssay Description:Estrogenic activity at estrogen receptor in human Ishikawa Var-1 cells assessed as stimulation of alkaline phosphatase activity measured by metabolis...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Transcriptional activation of ERalpha receptor expressed in CHO-K1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0700nMAssay Description:Agonist effect on transcriptional activation in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 24nM EC50: 0.0700nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0800nMAssay Description:Concentration required to activate luciferase expression in MCF-7-2a cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0850nMAssay Description:Agonist activity at human ERbeta expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0900nMAssay Description:Agonist activity at human full-length ERalpha receptor expressed in human HEC1 cells co-expressing (ERE)2-pS2-luc gene assessed as transcriptional ac...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0900nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0980nMAssay Description:Transcriptional activation of estrogen receptor beta in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-30...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0996nMAssay Description:Induction of pS2 mRNA expression in human MCF-7 mammary carcinoma cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at ERalpha expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Activation of ERalpha in human MCF7/2a cells by luciferase reporter gene assay relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataEC50: 0.107nMAssay Description:Agonist activity at GAL4 DNA binding domain fused full-length chimeric estrogen receptor alpha (unknown origin) by FRET-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.123nMAssay Description:Agonist activity at human ERalpha expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ER-alpha-mediated transcriptional activit...More data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonist activity at full-length human estrogen receptor beta expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Effect on ERbeta in rat ovary granulosa cell line transfected with ER responsive luciferase reporterMore data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Agonist activity at human ERalpha expressed in U2OS cells coexpressing pCMX-hSRC3 assessed as luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.151nMAssay Description:Agonist activity at GAL4 DNA binding domain fused full-length chimeric estrogen receptor beta (unknown origin) by FRET-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Agonist activity at human ERalpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by ERE-luciferase reporter gene t...More data for this Ligand-Target Pair
Affinity DataEC50: 0.180nMAssay Description:Affinity for estrogen receptor of human MCF-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human ERbeta expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Estrogenic activity at estrogen receptor alpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-Nitrophenol pho...More data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.25nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
