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Found 7 of ec50 for monomerid = 21342
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  15nMAssay Description:Functional potency at the rat 5-hydroxytryptamine 2A receptor as effective concentration EC50 for stimulating Phosphoinositide accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  9.80nMAssay Description:Tested for its ability to activate phospholipase C by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  9.80nMAssay Description:Activity at rat 5HT2A receptor assessed as 5HT-stimulated IP3 accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assa...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent a...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair