Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ec50 for monomerid = 22566
TargetHistamine H4 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human H4R expressed in human U2OS cells assessed as recruitment of beta-arrestin after 2 hrs by PathHunter beta-galactosidase enz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataEC50:  741nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataEC50:  794nMAssay Description:Agonist activity at mouse H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) assessed as increase in beta-arrestin recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed