Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ki for monomerid = 22851
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22851(1,2-Dione-Based Compound, 8 | 1,2-dihydronaphthale...)
Affinity DataKi:  320nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22851(1,2-Dione-Based Compound, 8 | 1,2-dihydronaphthale...)
Affinity DataKi:  930nM ΔG°:  -8.22kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22851(1,2-Dione-Based Compound, 8 | 1,2-dihydronaphthale...)
Affinity DataKi:  2.29E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22851(1,2-Dione-Based Compound, 8 | 1,2-dihydronaphthale...)
Affinity DataKi:  2.40E+3nM ΔG°:  -7.66kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed