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Found 11 of ic50 for monomerid = 22893
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50:  40nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50:  650nMAssay Description:Inhibition of guinea pig acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50:  2.30E+3nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50:  3.40E+3nMAssay Description:Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of Calcein-AM efflux in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of P-glycoprotein using calcein-AM assay transfected in porcine PBCECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Mus musculus (Mouse))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed