Compile Data Set for Download or QSAR
maximum 50k data
Found 31 of ki for monomerid = 25877
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha3-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  5.30nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21nMAssay Description:Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21nMAssay Description:Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha4-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21.4nM ΔG°:  -9.72kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21.4nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  25.8nM ΔG°:  -9.62kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  26nMAssay Description:Binding affinity for human GABA-A receptor alpha-3-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  26nMAssay Description:Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  26nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  26nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha6-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28nMAssay Description:Binding affinity for human GABA-A receptor alpha-1-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28nMAssay Description:Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.4nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.4nM ΔG°:  -9.56kcal/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.8nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha6-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.8nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  29nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha2-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  29nMAssay Description:Binding affinity against Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  29nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  29nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  53nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  53nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha3-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed