Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Angelini Santa Palomba Research Center
Curated by ChEMBL
Angelini Santa Palomba Research Center
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Antagonist activity at human 5HT4ER expressed in CHO cells assessed as reduction in cAMP levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 3 receptor in rat enthorinal cortex using [3H]-LY 278584 as radioligandMore data for this Ligand-Target Pair