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Found 15 of ic50 for monomerid = 29644
TargetD(1A)/D(2) dopamine receptor(BOVINE)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  25nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  27nMAssay Description:Compound was tested for inhibitory binding activity against dopamine receptor in rat striatal membranes using [3H]HAL as the radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Debrecen

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  87nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  182nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]spiperone binding dopamine receptor at 1 uMMore data for this Ligand-Target Pair
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  302nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  4.38E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  9.81E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  9.81E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  1.34E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  1.46E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  1.89E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA dC->dU-editing enzyme APOBEC-3G(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  2.62E+4nMT: 2°CAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEukaryotic translation initiation factor 4 gamma 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  6.40E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed