TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to recombinant MMP1More data for this Ligand-Target Pair
Affinity DataKi: 0.530nM ΔG°: -12.5kcal/mole IC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to recombinant MMP13More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).Checked by AuthorMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of matrix metalloprotease-8 (MMP-8).Checked by AuthorMore data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Binding affinity to recombinant MMP3More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 154nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity to recombinant TACEMore data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 527nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair