Affinity DataEC50: >1.00E+4nMAssay Description:Functional activity against adenosine A1 receptor from rat atria.More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Partial agonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as intrinsic activity by measuring cell index change withi...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activitty at Adenosine A1 receptor of rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 3.61E+5nMAssay Description:Agonist activity at human recombinant adenosine receptor A2b by cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at human adenosine A2a receptor expressed in CHO cells assessed as stimulation of cAMP formation after 24 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as stimulation of [3H]cAMP levels by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of [3H]cAMP levels by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 6.31E+5nMAssay Description:Agonist activity at human Adenosine A1 receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphai1 after 16 hrs by beta galactosidase r...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Adenosine A2A receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...More data for this Ligand-Target Pair
Affinity DataEC50: 6.31E+6nMAssay Description:Agonist activity at human Adenosine A2B receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells by GTPPgammaS binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 613nMAssay Description:Agonist activity at human adenosine A3 receptor expressed in CHO cells by GTPPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as effect on cAMP production by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.44E+3nMAssay Description:Binding against human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >100nMAssay Description:[S]GTP gamma-S binding against adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataEC50: 2.46E+4nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 115nMAssay Description:Functional activity against adenosine A2a receptor from rat aorta.More data for this Ligand-Target Pair
Affinity DataEC50: 2.13E+5nMAssay Description:Effective concentration for cAMP production in CHO-KI cells stably transfected with human adenosine A2B receptor cDNAMore data for this Ligand-Target Pair
Affinity DataEC50: 115nMAssay Description:Functional activity at Adenosine A2A receptor as vasorelaation of rat aortaMore data for this Ligand-Target Pair